New research published in this week's PLoS Medicine reveals that by living a physically active lifestyle, the genetic predisposition to obesity caused by the 'fat mass and obesity associated' (FTO) gene can be significantly reduced. The large international collaboration was led by Ruth Loos from the Medical Research Council Epidemiology Unit in Cambridge, UK, and showed that the effect of the FTO gene on obesity risk is nearly 30% weaker among physically active adults compared with those who are physically inactive.
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